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Transcriptome analysis from a small number of neurons purified from the aged mouse brain
21 May 2018
The Minichiello Group in collaboration with the Nerlov laboratory and FACS facility at the MRC Weatherall Institute of Molecular Medicine, has established new methods to isolate brain neurons from the adult and aged mouse. This makes it possible to perform unbiased studies of aging brain neurons from relatively…
The heart’s own adrenaline-producing cells can control heart rhythm
4 May 2018
The group led by Ming Lei has discovered that the heart can regulate its own rhythm by releasing adrenaline (epinephrine) from a specialised kind of heart muscle cell that contains the enzyme that makes adrenaline.
Rhythmic networks in the brain that help us find our way in the world
18 April 2018
The Somogyi group discovered a rhythmic subcortical inhibitory (GABAergic) nerve cell population in a part of the mouse brain called the medial septum that projects to both the dorsal presubiculum and entorhinal cortex but avoids the hippocampus. As set out in a recent paper published in eLife, the group name…
Growing up as a Pharmacologist
26 October 2017
Professor David Smith reflects on a research career which spans over fifty years