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Von der chemischen Mutagenese zur Postexpressions‐Mutagenese: eine 50 Jahre währende Odyssee
AbstractDie ortsspezifische (Gen‐)Mutagenese ist das wichtigste Verfahren zur Umwandlung eines Protein‐Aminosäurerestes in einen anderen. Bis vor kurzem war diese Strategie auf die zwanzig Standardaminosäuren beschränkt. Die ständige Weiterentwicklung der Stopp‐Codon‐Suppression und verwandter Techn…
Trehalose-6-phosphate signaling regulates lateral root formation in Arabidopsis thaliana.
Plant roots explore the soil for water and nutrients, thereby determining plant fitness and agricultural yield, as well as determining ground substructure, water levels, and global carbon sequestration. The colonization of the soil requires investment of carbon and energy, but how sugar and energy signaling ar…
Extracellular vesicle integrins act as a nexus for platelet adhesion in cerebral microvessels.
Circulating extracellular vesicles (EVs) regulate signaling pathways via receptor-ligand interactions and content delivery, after attachment or internalization by endothelial cells. However, they originate from diverse cell populations and are heterogeneous in composition. To determine the effects of specific surfa…