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What's new

New Akerman group paper reveals links between sleep, synaptic inhibition, and the plastic changes that underlie learning in the brain

Pharmacology researchers have discovered a key mechanism linking sleep and wake to synaptic plasticity in the brain, shedding light on how learning and memory may be affected by rest. Their study, published by Alfonsa et al. in the journal Current Biology, reveals that intracellular chloride levels shift during sleep and wakefulness, influencing synaptic plasticity processes in the brain’s cortex.

Professor Ben Davis awarded 2025 Claude S Hudson Award

Congratulations to Professor Ben Davis who has been announced as the recipient of the 2025 Claude S Hudson Award, presented by the American Chemical Society (ACS).

Anthony group research offers new treatment hope for ALS patients

New research, led by the Anthony Group in Pharmacology and funded by GeNeuro, suggests a pathway to a new precision medicine approach for patients with amyotrophic lateral sclerosis (ALS). The groundbreaking findings were presented at the 35th International Symposium on ALS/MND, which took place in Montreal, Canada, from 6-8 December 2024.

Parrington group paper reveals role for TPC1 channels in mTORC1 activity

New research published by the Parrington group help further understand the link between mTORC1 and endolysosomal ion channels, and reveal that TPC1 controls melanoma progression and represents a potential therapeutic target.

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