Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.
Garland dora science signaling cover july 2017

Professors Chris Garland and Kim Dora are leading authors on a new paper published this week in the journal 'Science Signaling' entitled "Voltage-dependent Ca2+ entry into smooth muscle during contraction promotes endothelium-mediated feedback vasodilation in arterioles". Research conducted by the group found that Ca2+ entry into vascular smooth muscle activates Ca2+ signaling in the endothelium to protect tissue blood flow. These results resolve a long-standing controversy over how vascular smooth muscle cells communicate with endothelial cells to trigger feedback vasodilation.