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Irradiation of a mixture of 4-methoxyphenacyl-caged (S)-glutamate and 4,5-dimethoxy-2-nitrobenzyl-caged γ-amino butyric acid (GABA) on neurons, at ~260 nm, evokes selective photorelease of (S)-glutamate (Glu) whereas photolysis at 405 nm causes selective photorelease of GABA.

Original publication

DOI

10.1039/c1cc15135e

Type

Journal article

Journal

Chem Commun (Camb)

Publication Date

18/01/2012

Volume

48

Pages

657 - 659

Keywords

Animals, Excitatory Amino Acid Antagonists, GABA Antagonists, Glutamates, Hippocampus, Magnetic Resonance Spectroscopy, Neurons, Neurotransmitter Agents, Patch-Clamp Techniques, Photochemistry, Photolysis, Receptors, GABA, Receptors, Glutamate, Synaptic Transmission, Ultraviolet Rays, gamma-Aminobutyric Acid