Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Acid hydrolysis of myo-inositol 1,3,5-orthobenzoate leads regioselectively to 2-O-benzoyl-myo-inositol via a 1,2-bridged 2'-phenyl-1',3'-dioxolan-2'-ylium ion observed by 1H and 13C NMR spectroscopy, providing the precursor for a highly efficient route to the anticancer agent myo-inositol 1,3,4,5,6-pentakisphosphate.

Original publication

DOI

10.1039/b605392k

Type

Journal article

Journal

Chem Commun (Camb)

Publication Date

28/07/2006

Pages

2989 - 2991

Keywords

Acids, Antineoplastic Agents, Hydrolysis, Inositol Phosphates, Magnetic Resonance Spectroscopy, Molecular Conformation, Stereoisomerism