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Syntheses of myo-inositol 1,4,6-trisphosphorothioate and 1,3,4-trisphosphorothioate from myo-inositol are described; these trisphosphorothioates, derived from structure-activity considerations of myo-inositol 1,3,4,6-tetrakisphosphate, are low intrinsic activity partial agonists at the platelet Ins(1,4,5)P 3 receptor. © 1995.

Original publication

DOI

10.1016/0960-894X(95)00012-I

Type

Journal article

Journal

Bioorganic and Medicinal Chemistry Letters

Publication Date

02/02/1995

Volume

5

Pages

203 - 208