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Nucleosides are glycosylamines that structurally form part of nucleotide molecules, the building block of DNA and RNA. Both nucleosides and nucleotides are vital components of all living cells and involved in several key biological processes. Some of these nucleosides have been obtained from a variety of marine resources. Because of the biological importance of these compounds, this review covers 68 marine originated nucleosides and their synthetic analogs published up to June 2014. The review will focus on the structures, bioactivities, synthesis and biosynthetic processes of these compounds.

Original publication

DOI

10.3390/md12125817

Type

Journal article

Journal

Mar Drugs

Publication Date

02/12/2014

Volume

12

Pages

5817 - 5838

Keywords

Animals, Biological Factors, Humans, Marine Biology, Nucleosides, Nucleotides