Phosphonates and thiophosphonates as sulfate surrogates: synthesis of estrone 3-methylthiophosphonate, a potent inhibitor of estrone sulfatase
Howarth NM., Cooper G., Purohit A., Duncan L., Reed MJ., Potter BV.
Estrone 3-phosphonaters and thiophosphonates have been synthesised as analogues of estrone 3-sulfate and exhibit potent activity as competitive inhibitors of estrone sulfatase, a potential therapeutic target in treatment of breast cancer. © 1993.