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Estrone 3-phosphonaters and thiophosphonates have been synthesised as analogues of estrone 3-sulfate and exhibit potent activity as competitive inhibitors of estrone sulfatase, a potential therapeutic target in treatment of breast cancer. © 1993.

Original publication

DOI

10.1016/S0960-894X(01)80900-8

Type

Journal article

Journal

Bioorganic and Medicinal Chemistry Letters

Publication Date

01/01/1993

Volume

3

Pages

313 - 318