The synthesis of the enantiomers of 2,2-difluoro-2-deoxy-myo-inositol 1,4,5-trisphosphate is reported. L-2,2-difluoro-2-deoxy-myo-inositol 1,4,5-trisphosphate is a potent inhibitor of 3-kinase and 5-phosphatase. © 1991.

Original publication

DOI

10.1016/S0960-894X(01)81052-0

Type

Journal article

Journal

Bioorganic and Medicinal Chemistry Letters

Publication Date

01/01/1991

Volume

1

Pages

705 - 710