Synthesis of L-chiro-inositol 1,4,6-trisphosphorothioate, a potent and selective inhibitor of myo-inositol 1,4,5-trisphosphate 5-phosphatase
Liu C., Safrany ST., Nahorski SR., Potter BV.
L-chiro-inositol 1,4,6-trisphosphate and trisphosphorothioate have been synthesized from L-quebrachitol; the trisphosphorothiate is the most potent inhibitor of Ins(1,4,5)P3 5-phosphatase yet discovered. © 1992.