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Methyllycaconitine (MLA) has been isolated from Garden Hybrid Delphinium and purified by vacuum liquid chromatography. 13 C NMR and optical rotation have been used to characterize the absolute configuration of the methylsuccinimide moiety as S. Ligand binding assays confirmed the potency of MLA and its selectivity for α-bungarotoxin-sensitive neuronal nicotinic acetylcholine receptors. © 1994.

Original publication

DOI

10.1016/S0040-4039(00)78476-0

Type

Journal article

Journal

Tetrahedron Letters

Publication Date

14/11/1994

Volume

35

Pages

8701 - 8704