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The regioselective acylation of 18-O-desmethylaconitine has been achieved with isatoic anhydride to afford the corresponding anthranilate ester, an analogue of inuline. The aniline nitrogen was then incorporated into an S-methylsuccinimide moiety, to afford a novel methyllycaconitine/aconitine hybrid alkaloid. © 1994.

Original publication

DOI

10.1016/S0040-4039(00)76911-5

Type

Journal article

Journal

Tetrahedron Letters

Publication Date

16/05/1994

Volume

35

Pages

3371 - 3374