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The synthesis of myo-inositol 1,4,6-trisphosphate from myo-inositol is described; this novel trisphosphate is a potent Ca 2+ -mobilising agonist at the Ins(1,4,5)P 3 receptor and is derived from structure-activity considerations of myo-inositol 1,3,4,6-tetrakisphosphate. © 1993.

Original publication

DOI

10.1016/S0960-894X(01)80723-X

Type

Journal article

Journal

Bioorganic and Medicinal Chemistry Letters

Publication Date

01/01/1993

Volume

3

Pages

2599 - 2604