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Lycoctonine has been acylated to afford sequentially inuline, delsemine analogues and methyllycaconitine using isatoic anhydride followed by S-(-)-methylsuccinic anhydride. This protocol is a rapid, facile method for the regiospecific introduction of the anthranilate ester moiety found in potent nicotinic acetylcholine receptor antagonists. © 1994.

Original publication

DOI

10.1016/S0040-4039(00)78477-2

Type

Journal article

Journal

Tetrahedron Letters

Publication Date

14/11/1994

Volume

35

Pages

8705 - 8708