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The synthesis of N 1 -[(1S,3R)-3-(hydroxymethyl)cyclopent-1-yl]inosine (11) via a cyclocondensation route is reported. Regioselective bisphosphorylation of the primary 5'-hydroxyl groups leads to a carbocyclic, inosine analogue of seco adenosine 5'-diphosphate ribose(3).

Original publication

DOI

10.1016/S0040-4039(97)01175-1

Type

Journal article

Journal

Tetrahedron Letters

Publication Date

28/07/1997

Volume

38

Pages

5371 - 5374