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Synthesis of myo-insoitol 1,4,5-triphosphate and myo-inositol 1,4,-bisphosphate-5-phosphorothioate, a phosphatase-resistant analogue of a biological second messenger, have been accomplished using a novel combination of P < sup > III < /sup > and P < sup > V < /sup > chemistry and a new deprotection method for the 2,2,2-trichloroethyl group.

Original publication

DOI

10.1039/C39890000269

Type

Journal article

Journal

Journal of the Chemical Society, Chemical Communications

Publication Date

01/01/1989

Pages

269 - 271