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Publications

The TMEM16A channel as a potential therapeutic target in vascular disease.

Al-Hosni R. et al, (2024), Curr Opin Nephrol Hypertens, 33, 161 - 169

Identification of determinants of lipid and ion transport in TMEM16/anoctamin proteins through a Bayesian statistical analysis.

Moran O. and Tammaro P., (2024), Biophys Chem, 308

The TMEM16A anion channel as a versatile regulator of vascular tone.

Tammaro P., (2023), Sci Signal, 16

The pharmacology of the TMEM16A channel: therapeutic opportunities.

Al-Hosni R. et al, (2022), Trends Pharmacol Sci

The Ca2+-gated channel TMEM16A amplifies capillary pericyte contraction and reduces cerebral blood flow after ischemia

Korte N. et al, (2022), Journal of Clinical Investigation

TMEM16A channel is a key regulator of cerebral blood flow at the capillary level

Ilkan Z. et al, (2022), BIOPHYSICAL JOURNAL, 121, 176A - 176A

The Ca2+-gated Cl- channel TMEM16A amplifies capillary pericyte contraction reducing cerebral blood flow after ischemia

Korte N. et al, (2022)

Polymodal Control of TMEM16x Channels and Scramblases

Agostinelli E. and Tammaro P., (2022), International Journal of Molecular Sciences, 23

An outer-pore gate modulates the pharmacology of the TMEM16A channel.

Dinsdale RL. et al, (2021), Proc Natl Acad Sci U S A, 118

Ion channels as convergence points in the pathology of pulmonary arterial hypertension.

Jouen-Tachoire TRH. et al, (2021), Biochem Soc Trans

The Molecular Basis of the Regulation of the TMEM16A Ca2+-Activated Cl- Channel by the Lysosomal NPC1 Protein

Scofano LF. et al, (2021), BIOPHYSICAL JOURNAL, 120, 247A - 247A

Lipid-mediated control of the TMEM16A Ca2+- gated Cl- channel by the lysosomal NPC1 protein

Scofano LF. et al, (2021), BRITISH JOURNAL OF PHARMACOLOGY, 178, 414 - 414

Molecular Mechanism of Modulation of the TMEM16A Channel by Anthracene-9-Carboxylic Acid: Implications for Channel Gating

Dinsdale R. et al, (2020), BIOPHYSICAL JOURNAL, 118, 325A - 325A

Control of cerebral blood flow by capillary pericytes in Alzheimer's disease

Korte N. et al, (2019), ACTA PHYSIOLOGICA, 227

The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.

Bushell SR. et al, (2019), Nat Commun, 10

The Ca2+-gated Cl- channel TMEM16A is a crucial mediator of pericyte contraction in the CNS microvasculature

Korte N. et al, (2019), GLIA, 67, E649 - E649

Inhibition of TMEM16A by Docosahexaenoic Acid Plays a Crucial Role in Blood Vessel Relaxation

Acheson KE. and Tammaro P., (2019), BIOPHYSICAL JOURNAL, 116, 172A - 172A

Defining the ionic mechanisms of optogenetic control of vascular tone by channelrhodopsin-2.

Rorsman NJG. et al, (2018), Br J Pharmacol, 175, 2028 - 2045

Contrasting effects of phosphatidylinositol 4,5-bisphosphate on cloned TMEM16A and TMEM16B channels.

Ta CM. et al, (2017), Br J Pharmacol, 174, 2984 - 2999

Mechanism of allosteric activation of TMEM16A/ANO1 channels by a commonly used chloride channel blocker.

Ta CM. et al, (2016), Br J Pharmacol, 173, 511 - 528

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