Research groups
Colleges
Daniel C Anthony
Professor of Experimental Neuropathology
- Fellow of Somerville College
- Honorary Professor, University of Southern Denmark
- Fellow of the British Pharmacological Society
Daniel Anthony, a specialist in inflammatory disease, leads the Experimental Neuropathology Laboratory at the University of Oxford. As a Fellow of Somerville College and an Honorary Professor at the University of Southern Denmark, he has developed a niche in understanding how systemic inflammation influences the outcomes of both acute and chronic brain injuries and infections. His research interests also focus on the role of circulating extracellular vesicles in the pathogenesis of CNS diseases and the contribution of cytokine production to neuropsychiatric disorders.
Professor Anthony's career began with a Ph.D. from University College London in 1994, after which he joined Professor Hugh Perry in Oxford on a British Biotech Fellowship to explore metalloproteinase expression in the CNS. His work has led to the identification of novel biomarkers for diagnosing disease and predicting progression, leveraging a combination of in vivo biology, molecular biology, immunohistochemistry, MRI and PET imaging, and metabolomics. After a stint at the University of Southampton, where he was a Lecturer in Neurobiology, he returned to Oxford in 2004, where he continues to explore the neurobiology of inflammation with research collaborations throughout the world. In 2015, he was awarded a personal Chair in Experimental Neuropathology, and he was made a Fellow of the British Pharmacological Society in 2020.
Recent publications
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Lesion level and severity acutely influence metabolomic profiles in spinal cord injury.
Journal article
Yates AG. et al, (2026), J Neuropathol Exp Neurol, 85, 24 - 38
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The effects of elevated serum lactate on measures of apparent cerebral metabolism and perfusion in the anesthetised rodent brain
Preprint
Radford-Smith D. et al, (2025)
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Multi-Omics Modelling of Plasma pTau181, GFAP, and Metabolic Features Enables Risk Stratification in Prodromal Alzheimer’s Disease
Preprint
Kacerova T. et al, (2025)
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Elevated Acetylation of MFN2 is Accompanied by the Disruption of Mitochondrial Energy Metabolism and Inflammation in a Mouse Model of Depression.
Journal article
Xie X. et al, (2025), Mol Neurobiol, 62, 14167 - 14175
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Period3 modulates the NAD+-SIRT3 axis to alleviate depression-like behaviour by enhancing NAMPT activity in mice.
Journal article
Xie X. et al, (2025), J Adv Res, 77, 309 - 320
