Associate Professor in Cellular and Molecular Pharmacology
- Fellow and Tutor in Physiological Sciences
- Fellow and College Lecturer at Worcester
PLCζ is the physiological trigger of the Ca2+oscillations that induce embryogenesis in mammals but conception can occur in its absence.
Hachem A. et al, (2017), Development, 144, 2914 - 2924
Synthesis of the Ca2+-mobilizing messengers NAADP and cADPR by intracellular CD38 enzyme in the mouse heart: Role in β-adrenoceptor signaling.
Lin WK. et al, (2017), J Biol Chem, 292, 13243 - 13257
Ca2+release via two-pore channel type 2 (TPC2) is required for slow muscle cell myofibrillogenesis and myotomal patterning in intact zebrafish embryos.
Kelu JJ. et al, (2017), Dev Biol, 425, 109 - 129
Metabolic alterations derived from absence of Two-Pore Channel 1 at cardiac level.
Garcia-Rua V. et al, (2016), J Biosci, 41, 643 - 658
Is medicine ready for clinical CRISPR?: Using precision genome editing to treat or prevent human disease may require several leaps of faith
Parrington J., (2016), Scientist, 30