Nuno Raimondo
Associate Professor, Department of Cell and Biological Systems, Penn State Cancer Institute
- Visiting Fellow, Oxford Department of Pharmacology
My lab focuses on organelle crosstalk, and employs cellular and mouse models of organelle defects (mitochondria, lysosomes, peroxisomes, ER). The ultimate goal is to harness the signaling and metabolic environment to design novel strategies to target mitochondrial and lysosomal diseases, for which there is no cure, and to explore the interface between organelle biology, cellular signaling and metabolism. Because mitochondria and lysosomes get progressively dysfunctional during aging, our findings have broad application to age-related diseases such as cancer and neurodegenerative syndromes.