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Rebecca M A Sitsapesan
Professor of Pharmacology
- Fellow in Medicine and Physiology, Hertford College
I hold a BSc in Pharmacology (Aberdeen), an MSc in Cardiovascular Studies (Leeds) and a PhD in Cardiac Physiology and Pharmacology (Strathclyde). My post-doctoral research into ion-channel biophysics began at the University of Glasgow and continued at the National Heart & Lung Institute at Imperial College, London.
In 1991, I was awarded a British Heart Foundation Basic Science Lectureship to investigate the function of cardiac intracellular Ca2+-release channels and a University Lectureship at Imperial College. I moved to Bristol in 2001 and was promoted to Professor of Pharmacology in 2011. In August 2013, I became Professor of Pharmacology at the University of Oxford.
Dampened activity of ryanodine receptor channels in mutant skeletal muscle lacking TRIC-A.
El-Ajouz S. et al, (2017), J Physiol, 595, 4769 - 4784
Synthesis of the Ca(2+)-mobilizing messengers, NAADP and cADPR, by intracellular CD38 enzyme in mouse heart: role in β-adrenoceptor signaling.
Lin WK. et al, (2017), J Biol Chem
Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2).
Grieben M. et al, (2017), Nat Struct Mol Biol, 24, 114 - 122
Is there something fishy about the regulation of the ryanodine receptor in the fish heart?
Shiels HA. and Sitsapesan R., (2015), Experimental Physiology, 100, 1412 - 1420
Subconductance gating and voltage sensitivity of sarcoplasmic reticulum K(+) channels: a modeling approach.
Matyjaszkiewicz A. et al, (2015), Biophys J, 109, 265 - 276