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My connections

Sophie Avery

DPhil Student

  • Wellcome Trust Doctoral Programme in Neuroscience
  • Akerman Group

A fundamental question in neuroscience is how neurons establish their functional identity and specific synaptic connections with other cells. However, very little is known about how, or when, the functional identity and connectivity of an individual neuron becomes constrained during its development.

Recent technical advances now make it possible to label different populations of neurons in the brain, and this work has generated exciting discoveries into the processes by which neurons form functional networks.

My work builds upon the observation that excitatory cortical neurons are generated from multiple progenitor pools within the ventricular zones of the embryonic brain, which may have important implications for neuronal diversity and specialisation within the cortical network.

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